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NAK / TBK1 antibody

Cat. No. GTX28121

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Mouse, Rat
Package
100 μg ($479)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5-1 μg/ml
Not tested in other applications.

Calculated MW

84 kDa. ( Note )

Product Note

This antibody recognizes an epitope at the C-terminus of human, mouse, and rat NAK/TBK1 (NF-κB Activating Kinase and TANK-Binding Kinase 1). This antibody does not cross-react with IKKα, IKKβ, IKKε, or IKKγ.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to aa 712-727 of human NAK/TBK1. This sequence is identical to that of mouse NAK/TBK1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FTDALS4 , NAK , T2K , TANK binding kinase 1 , TBK1

Cellular Localization

Cytoplasm

Background

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

Database

Research Area

REFERENCE

There are currently no references for NAK / TBK1 antibody (GTX28121). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for NAK / TBK1 antibody (GTX28121). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 479