GeneTex
United States (US)

NALP1 antibody [Nalpy1-4]

Cat No. GTX16091

Host Mouse
Clonality Monoclonal
Clone Name Nalpy1-4
Isotype IgG1
Application WB, ICC/IF, IHC-P, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1,000
ICC/IF 1 μg/mL
IHC-P Assay dependent
IP Assay dependent

Note :

ICC/IF
293T cells transfected with human NALP1?were fixed with 4% paraformaldehyde.

Not tested in other applications.

Calculated MW

166 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALP1 (monoclonal Nalpy1-4) antibody was raised against recombinant human NALP1 (NACHT-, LRR- and PYD-) containing protein.

Purification

Purified IgG1
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nlr Family Pyrin Domain Containing 1,Aiadk,Card7,Cided,Clr17.1,Defcap,Defcap-L/S,Mspc,Nac,Nalp1,Pp1044,Slev1,Vamas1,Nlrp1

Cellular Localization

Cytoplasmic

Background

This gene encodes a member of the Ced 4 family of apoptosis proteins. Ced family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N terminal pyrin like motif, which is possibly involved in protein protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for NALP1, but the biological validity of some variants has not been determined.

Database

Research Area

Package List Price ($)
$ 319