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NALP1 antibody

Anti-NALP1 antibody used in Western Blot (WB). GTX04532
Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04532
Anti-NALP1 antibody used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX04532

Cat. No. GTX04532

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, ELISA, IHC-P (cell pellet)

Reactivity

Human
Package
100 μg ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-4 μg/mL
ICC/IF 20 μg/mL
ELISA Assay dependent
IHC-P (cell pellet) 10 μg/mL
Not tested in other applications.

Calculated MW

166 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. The immunogen is located within the last 50 amino acids of NALP1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NLR family pyrin domain containing 1 , AIADK , CARD7 , CIDED , CLR17.1 , DEFCAP , DEFCAP-L/S , MSPC , NAC , NALP1 , PP1044 , SLEV1 , VAMAS1

Cellular Localization

Cytoplasm, cytosol , Cytoplasm , Nucleus

Background

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-NALP1 antibody used in Western Blot (WB). GTX04532

GTX04532 WB Image

WB analysis of U937 whole cell lysate using GTX04532 NALP1 antibody.
Dilution :
Lane 1 : 1 μg/mL
Lane 2 : 2 μg/mL
Lane 3 : 4 μg/mL

Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04532

GTX04532 ICC/IF Image

ICC/IF analysis of K562 cells using GTX04532 NALP1 antibody.
Dilution : 20 μg/mL

Anti-NALP1 antibody used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX04532

GTX04532 IHC-P (cell pellet) Image

IHC-P (cell pellet) analysis of K562 cells using GTX04532 NALP1 antibody.
Dilution : 10 μg/mL

REFERENCE

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REVIEW

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Package List Price ($)
$ 429