APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 10 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10.The immunogen is located within the first 50 amino acids of NALP10.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
NLR family pyrin domain containing 10 , CLR11.1 , NALP10 , NOD8 , PAN5 , PYNOD
Cellular Localization
Cytoplasm,Cell membrane
Background
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
Database
Research Area
DATA IMAGES
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GTX85154 IHC-P Image
IHC-P analysis of human brain tissue using GTX85154 NALP10 antibody.
Working concentration : 20 μg/ml
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GTX85154 IHC-P Image
IHC-P analysis of human brain tissue using GTX85154 NALP10 antibody.
Working concentration : 10 μg/ml
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GTX85154 WB Image
WB analysis of human brain tissue lysate using GTX85154 NALP10 antibody.
Working concentration : 1 μg/ml
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REFERENCE
There are currently no references for NALP10 antibody (GTX85154). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NALP10 antibody (GTX85154). Be the first to share your experience with this product.
