GeneTex
United States (US)

NALP2 antibody, C-term

GTX88068_2680_WB_18121411_667.jpg

Cat No. GTX88068

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2μg/ml
Not tested in other applications.

Calculated MW

121 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88068-PEP).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KNPQLIIDTEKHHP, from the C Terminus (near) of the protein sequence according to NP_060322.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nlr Family Pyrin Domain Containing 2,Clr19.9,Nalp2,Nbs1,Pan1,Pypaf2,Nlrp2

Background

NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES
GTX88068_2680_WB_18121411_667.jpg

GTX88068 WB Image

WB analysis of HEK293 overexpressing human NLRP2 with DYKDDDDK tag using GTX88068 NALP2 antibody, C-term.
Lane A : primary antibody
Lane B : Mock-transfected HEK293 probed with primary antibody
Lane C : Tag antibody
Dilution : 1µg/ml
Loading : 10µg protein in RIPA buffer

Package List Price ($)
$ 329