GeneTex

  • Country / Location Selection

United States (US)

NALP2 antibody, C-term

Anti-NALP2 antibody, C-term used in Western Blot (WB). GTX88068

Cat. No. GTX88068

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all NALP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
Not tested in other applications.

Calculated MW

121 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88068-PEP).

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KNPQLIIDTEKHHP, from the C Terminus (near) of the protein sequence according to NP_060322.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NLR family pyrin domain containing 2 , CLR19.9 , NALP2 , NBS1 , PAN1 , PYPAF2

Cellular Localization

Cytoplasm

Background

This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Database

Research Area

DATA IMAGES

Anti-NALP2 antibody, C-term used in Western Blot (WB). GTX88068

GTX88068 WB Image

WB analysis of HEK293 overexpressing human NLRP2 with DYKDDDDK tag using GTX88068 NALP2 antibody, C-term.
Lane A : primary antibody
Lane B : Mock-transfected HEK293 probed with primary antibody
Lane C : Tag antibody
Dilution : 1μg/ml
Loading : 10μg protein in RIPA buffer

REFERENCE

There are currently no references for NALP2 antibody, C-term (GTX88068). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for NALP2 antibody, C-term (GTX88068). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399