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NAP2 antibody

Cat. No. GTX29554

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($449)
See all NAP2 products

APPLICATION

Application Note

Neutralization:To yield one-half maximal inhibition [ND50] of the biological activity of hNAP-2 (50 ng/ml), a concentration of 1.75 - 3.0 μg/ml of this antibody is required. ELISA:To detect hNAP-2 by direct ELISA (using 100μl/well antibody solution) a concentration of at least 0.5μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hNAP-2. Western Blot:To detect hNAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNAP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Calculated MW

14 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS pH7.4

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Highly pure (>98%) recombinant human NAP2 (human Neutrophil Activating Protein-2).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pro-platelet basic protein , B-TG1 , Beta-TG , CTAP-III , CTAP3 , CTAPIII , CXCL7 , LA-PF4 , LDGF , MDGF , NAP-2 , PBP , SCYB7 , TC1 , TC2 , TGB , TGB1 , THBGB , THBGB1

Cellular Localization

Secreted

Background

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 449