GeneTex
United States (US)

NBS1 antibody

KO/KD
GTX35197_20180822_WB_18121410_144.jpg
GTX35197_20180822_WB_1_18121410_150.jpg

Cat No. GTX35197

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

85 kDa kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% glycerol, 0.02% sodium azide

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBN (NP_002476.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AT V2 Antibody , P95 Antibody , ATV Antibody , AT V1 Antibody , nibrin Antibody , NBS Antibody , NBN Antibody

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
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DATA IMAGES
GTX35197_20180822_WB_18121410_144.jpg

GTX35197 WB Image

KO/KD

WB analysis of various samples using GTX35197 NBS1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX35197_20180822_WB_1_18121410_150.jpg

GTX35197 WB Image

KO/KD

WB analysis of wild type and NBS1 knockout cell lysate using GTX35197 NBS1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329