*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HeLa , HeLa (100 J/M2 UVC treatment and recovery for 4 hr)
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.97mg/ml(Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide corresponding to residues around human NBS1 (phospho Ser343). The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
AT-V1 antibody antibody , AT-V2 antibody antibody , ATV antibody antibody , NBN antibody antibody , NBS antibody antibody , NBS1 antibody antibody , P95 antibody antibody , nibrin antibody antibody
Nucleus (By similarity) , Telomere (By similarity)
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq]