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NCOA62 antibody, N-term

Anti-NCOA62 antibody, N-term used in Western Blot (WB). GTX77874
Anti-NCOA62 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77874
Anti-NCOA62 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77874

Cat. No. GTX77874

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μg ($399)
See all NCOA62 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human NCOA62.

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_424822

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SNW domain containing 1 , Bx42 , FUN20 , NCOA-62 , PRPF45 , Prp45 , SKIIP , SKIP , SKIP1

Cellular Localization

Nucleus

Background

This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-NCOA62 antibody, N-term used in Western Blot (WB). GTX77874

GTX77874 WB Image

WB analysis of Jurkat cells using GTX77874 SKIIP antibody at 0.2-1μg/ml.

Anti-NCOA62 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77874

GTX77874 IHC-P Image

IHC-P analysis of human lung tissue using GTX77874 SKIIP antibody at 4.0-8.0μg/ml.

Anti-NCOA62 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77874

GTX77874 IHC-P Image

IHC-P analysis of human intestine tissue using GTX77874 SKIIP antibody at 4.0-8.0μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399