APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
nuclear receptor corepressor 1 , N-CoR , N-CoR1 , PPP1R109 , TRAC1 , hN-CoR
Cellular Localization
Nucleus
Background
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
Database
Research Area
DATA IMAGES
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GTX83168 WB Image
WB analysis of truncated Trx-NCOR1 recombinant protein (1) using GTX83168 NCOR1 antibody [7A7A9].
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GTX83168 IHC-P Image
IHC-P analysis of human cerebra (left) and breast carcinoma tissue (right) using GTX83168 NCOR1 antibody [7A7A9].
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REFERENCE
There are currently no references for NCOR1 antibody [7A7A9] (GTX83168). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NCOR1 antibody [7A7A9] (GTX83168). Be the first to share your experience with this product.