GeneTex
United States (US)

NDE1 antibody [AT1F7]

GTX53751_WB_18121410_958.jpg

Cat No. GTX53751

Host Mouse
Clonality Monoclonal
Clone Name AT1F7
Isotype IgG1
Application WB, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500

Calculated MW

39 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human NDE1 (1-335aa) purified from E. coli

Purification

By protein-G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

nudE nuclear distribution E homolog 1 (A. nidulans) Antibody , LIS4 Antibody , HOM-TES-87 Antibody , NUDE1 Antibody , NUDE Antibody

Background

This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES
GTX53751_WB_18121410_958.jpg

GTX53751 WB Image

WB analysis of the NIH3T3 lysate (40ug) using NDE1 antibody.

Package List Price ($)
$ 319