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NDE1 antibody

Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347
Anti-NDE1 antibody used in Western Blot (WB). GTX33347
Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347
Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347

Cat No. GTX33347

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($329)
See all NDE1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NDE1 (NP_060138.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

nudE neurodevelopment protein 1 , HOM-TES-87 , LIS4 , MHAC , NDE , NUDE , NUDE1

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347

GTX33347 IHC-P Image

IHC-P analysis of rat brain tissue using GTX33347 NDE1 antibody.
Dilution : 1:100

Anti-NDE1 antibody used in Western Blot (WB). GTX33347

GTX33347 WB Image

WB analysis of various samples using GTX33347 NDE1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347

GTX33347 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX33347 NDE1 antibody.
Dilution : 1:100

Anti-NDE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33347

GTX33347 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX33347 NDE1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329