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United States (US)

NDUFV1 antibody

Anti-NDUFV1 antibody used in Western Blot (WB). GTX33351
Anti-NDUFV1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33351

Cat No. GTX33351

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

51 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NDUFV1 (NP_009034.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nadh:Ubiquinone Oxidoreductase Core Subunit V1,Ci-51K,Ci51Kd,Uqor1,Ndufv1

Background

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES
Anti-NDUFV1 antibody used in Western Blot (WB). GTX33351

GTX33351 WB Image

WB analysis of various samples using GTX33351 NDUFV1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NDUFV1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33351

GTX33351 ICC/IF Image

ICC/IF analysis of A549 cell using GTX33351 NDUFV1 antibody.
Blue : DAPI

Package List Price ($)
$ 329