*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
NEIL3 Polyclonal Antibody detects endogenous levels of NEIL3 protein.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Synthesized peptide derived from the C-terminal region of human NEIL3 at AA range: 460-540.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Nei Like Dna Glycosylase 3 , Fgp2 , Fpg2 , Nei3 , Zgrf3 , Hfpg2 , Hnei3 , Neil3
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]