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NEI3 antibody

Orthogonal
Anti-NEI3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55960
Anti-NEI3 antibody used in Western Blot (WB). GTX55960

Cat. No. GTX55960

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all NEI3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of NEI3. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nei like DNA glycosylase 3 , FGP2 , FPG2 , NEI3 , ZGRF3 , hFPG2 , hNEI3

Cellular Localization

Nucleus

Background

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-NEI3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55960

GTX55960 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX55960 NEI3 antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-NEI3 antibody used in Western Blot (WB). GTX55960

GTX55960 WB Image

WB analysis of human testis (A), HepG2 (B) whole cell lysates using GTX55960 NEI3 antibody.

REFERENCE

Application Reference

Liao W et al. Cancers (Basel) 2022; 15 (1) Pan-Cancer Landscape of NEIL3 in Tumor Microenvironment: A Promising Predictor for Chemotherapy and Immunotherapy.
Application : WB, IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399