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NEU1 antibody

Anti-NEU1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64524
Anti-NEU1 antibody used in Western Blot (WB). GTX64524

Cat. No. GTX64524

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all NEU1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 156-415 of human NEU1 (NP_000425.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2888601

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neuraminidase 1 , NANH , NEU , SIAL1

Cellular Localization

Cell membrane,Cytoplasmic vesicle,Lysosome

Background

The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-NEU1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64524

GTX64524 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64524 NEU1 antibody.
Dilution : 1:100

Anti-NEU1 antibody used in Western Blot (WB). GTX64524

GTX64524 WB Image

WB analysis of various sample lysates using GTX64524 NEU1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Eichner LJ et al. Cell Metab 2018; (Epub) Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399