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NF-H antibody [NAP4]

Anti-NF-H antibody [NAP4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82647
Anti-NF-H antibody [NAP4] used in Western Blot (WB). GTX82647

Cat. No. GTX82647

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NAP4

Isotype

 IgG1

Application

 WB, ICC/IF, IHC

Reactivity

 Human, Rat
Package
100 μl ($499)
See all NF-H products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

112 kDa. ( Note )

PROPERTIES

Form

Liquid

Preservative

10mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Bovine

Immunogen

Purified bovine NF-H

Purification

Total IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurofilament heavy , CMT2CC , NFH

Cellular Localization

Cytoplasm

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-NF-H antibody [NAP4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82647

GTX82647 ICC/IF Image

Immunostaining of human cerebellar cortex showing labeling of NF-H (brown) in basket cell axons surrounding the large Purkinje neurons.

Anti-NF-H antibody [NAP4] used in Western Blot (WB). GTX82647

GTX82647 WB Image

Western blot of rat cortex lysate showing specific immunolabeling of the ~200k NF-H protein using Neurofilament NF-H antibody [NAP4] (GTX82647).

REFERENCE

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REVIEW

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Package List Price ($)
$ 499