NF-H antibody [NEFL.H/2324R]

Cat. No. GTX02687

Host	Rabbit
Clonality	Monoclonal
Clone Name	NEFL.H/2324R
Isotype	IgG
Application	WB, IHC-P, FACS
Reactivity	Human, Mouse, Rat, Chicken, Pig
Package	100 μg ($529)

See all NF-H products

Datasheet

View product citations for antibody GTX02687 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1-2 μg/ml
IHC-P	1-2 μg/ml
FACS	1-2 μg/million cells
Note : IHC-P Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

112 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human NEFH protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurofilament heavy , CMT2CC , NFH

Cellular Localization

Cytoplasm

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Database

Gene ID: 4744 NEFH
UniProt: P12036 NEFH

Research Area

DATA IMAGES

GTX02687 IHC-P Image

IHC-P analysis of human cerebellum tissue section using GTX02687 NF-H antibody [NEFL.H/2324R].

GTX02687 WB Image

WB analysis of human brain tissue lysate using GTX02687 NF-H antibody [NEFL.H/2324R].

GTX02687 FACS Image

FACS analysis of HEK293 cells using GTX02687 NF-H antibody [NEFL.H/2324R].
Blue : Primary antibody
Red : Isotype control

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 529

Qty