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NF-L antibody [SPM204]

Anti-NF-L antibody [SPM204] used in IHC (Paraffin sections) (IHC-P). GTX34903

Cat. No. GTX34903

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SPM204

Isotype

 IgG1

Application

 ICC/IF, IHC-P

Reactivity

 Human, Rat, Bovine, Chicken, Pig
Package
100 μg ($529)
See all NF-L products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Neurofilament Purified from human brain

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CMT1F , CMT2E , NEFL , NF68 , NFL , PPP1R110 , neurofilament, light polypeptide , NF-L , NF-68 , neurofilament light , 68kDa Neurofilament Light

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-NF-L antibody [SPM204] used in IHC (Paraffin sections) (IHC-P). GTX34903

GTX34903 IHC-P Image

IHC-P analysis of cerebellum tissue using GTX34903 NF-L antibody [SPM204].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529