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NF-L antibody

Anti-NF-L antibody used in Western Blot (WB). GTX82644

Cat. No. GTX82644

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB, IHC

Reactivity

 Rat
Package
100 μl ($439)
See all NF-L products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

10mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Bovine

Immunogen

Preparation of bovine spinal cord NF-L

Purification

Total IgY fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurofilament light , CMT1F , CMT2E , CMTDIG , NF-L , NF68 , NFL , PPP1R110

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-NF-L antibody used in Western Blot (WB). GTX82644

GTX82644 WB Image

Western blot of rat cortex lysate showing specific immunolabeling of the ~68kD NF-L protein using GTX82644

REFERENCE

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REVIEW

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Package List Price ($)
$ 439