PBS pH 7.2, 1%BSA, sodium azide (0.02%, w/v)
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
2 mg/ml (Please refer to the vial label for the specific concentration.)
NFM protein was purified from bovine spinal cords following the method of Delacourte et al.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Human Neurofilament Medium Chain (NF-M) is a 102,448 dalton protein (916 amino acids) expressed in CNS and PNS neurons. This cytoskeletal protein is normally phosphorylated in vivo, and its extent of phosphorylation correlates with different states of axonal growth and stabilization. These observations have led to the hypothesis that the NF-M protein cross-links adjacent neurofilament strands, and contributes to the structural integrity of the axon.