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NFkB p100/p52 antibody [N1N3]

Anti-NFkB p100/p52 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX101151

Cat No. GTX101151

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Rat
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

Predict Reactivity

Human, Mouse, Bovine, Chicken(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human NFkB p100/p52. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

nuclear factor kappa B subunit 2 , CVID10 , H2TF1 , LYT-10 , LYT10 , NF-kB2 , p100 , p49/p100 , p52

Cellular Localization

Nucleus , Cytoplasm

Background

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM]

Database

Research Area

DATA IMAGES
Anti-NFkB p100/p52 antibody [N1N3] used in IHC (Paraffin sections) (IHC-P). GTX101151

GTX101151 IHC-P Image

NFkB p100/p52 antibody [N1N3] detects NFKB2 protein at cytoplasm in rat thymus by immunohistochemical analysis.
Sample: Paraffin-embedded rat lymph node.
NFkB p100/p52 antibody [N1N3] (GTX101151) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE
There are currently no references for NFkB p100/p52 antibody [N1N3] (GTX101151). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NFkB p100/p52 antibody [N1N3] (GTX101151). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf