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NFkB p65 antibody [NF-12]

Cat No. GTX10437

Host Mouse
Clonality Monoclonal
Clone Name NF-12
Isotype IgG1
Application WB, ICC/IF
Reactivity Human, Mouse
Package
50 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1,000
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Positive Control

mouse fibroblast cell line
PROPERTIES

Form

Liquid

Buffer

Ascites, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Mouse

Immunogen

recombinant mouse NF-κB p65 fragment (C-terminal, 151 amino acids).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

RELA proto-oncogene, NF-kB subunit , CMCU , NFKB3 , p65

Cellular Localization

Nucleus,Cytoplasm

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

REFERENCE
There are currently no references for NFkB p65 antibody [NF-12] (GTX10437). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NFkB p65 antibody [NF-12] (GTX10437). Be the first to share your experience with this product.