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NFkB p65 (phospho Ser468) antibody

Anti-NFkB p65 (phospho Ser468) antibody used in IHC (Paraffin sections) (IHC-P). GTX32256
Anti-NFkB p65 (phospho Ser468) antibody used in Western Blot (WB). GTX32256

Cat No. GTX32256

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

60 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of NFkB p65. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

RELA proto-oncogene, NF-kB subunit , CMCU , NFKB3 , p65

Cellular Localization

Nucleus,Cytoplasm

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES
Anti-NFkB p65 (phospho Ser468) antibody used in IHC (Paraffin sections) (IHC-P). GTX32256

GTX32256 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX32256 NFkB p65 (phospho Ser468) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-NFkB p65 (phospho Ser468) antibody used in Western Blot (WB). GTX32256

GTX32256 WB Image

WB analysis of TNFa-treated HeLa (A), LPS-treated NIH3T3 (B), rat brain (C) whole cell lysates using GTX32256 NFkB p65 (phospho Ser468) antibody.

REFERENCE
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REVIEW
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