*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody reacts with NHERF1/EBP50 phosphoprotein of 50 kDa.
15mM Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Bacterially produced recombinant full-length human NHERF1.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
EBP50 , NHERF , NHERF1 , NPHLOP2 , SLC9A3 regulator 1 , SLC9A3R1 , NHE-RF1
Cytoplasm,Apical cell membrane,Endomembrane system,Cell projection,Filopodium,Ruffle,Microvillus
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]