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NIPSNAP antibody

Anti-NIPSNAP antibody used in IHC (Paraffin sections) (IHC-P). GTX85406
Anti-NIPSNAP antibody used in IHC (Paraffin sections) (IHC-P). GTX85406
Anti-NIPSNAP antibody used in Western Blot (WB). GTX85406

Cat. No. GTX85406

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all NIPSNAP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)

Product Note

This antibody is specific for NIPSNAP Internal

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NIPSNAP antibody was raised against a 19 amino acid synthetic peptide from near the center of human NIPSNAP.The immunogen is located within amino acids 130 - 180 of NIPSNAP.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nipsnap homolog 1

Background

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

Database

Research Area

DATA IMAGES

Anti-NIPSNAP antibody used in IHC (Paraffin sections) (IHC-P). GTX85406

GTX85406 IHC-P Image

IHC-P analysis of human brain tissue using GTX85406 NIPSNAP antibody.
Working concentration : 2.5 μg/ml

Anti-NIPSNAP antibody used in IHC (Paraffin sections) (IHC-P). GTX85406

GTX85406 IHC-P Image

IHC-P analysis of human brain tissue using GTX85406 NIPSNAP antibody.
Working concentration : 20 μg/ml

Anti-NIPSNAP antibody used in Western Blot (WB). GTX85406

GTX85406 WB Image

WB analysis of human brain tissue lysate using GTX85406 NIPSNAP antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399