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NK1.1 antibody [PK136] (Azide free)

Cat. No. GTX74814

Reference 9

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PK136

Isotype

 IgG2a

Application

 IHC-P, IHC-Fr, FACS, IP, Activation, Depletion, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($409)
See all NK1.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Activation Assay dependent
Depletion Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Spleen and bone marrow cells from CE mice

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_378270

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NKRP1-B Antibody , KLRB1D Antibody , LY55B Antibody , LY55D Antibody , KLRB1B Antibody , NKRP1D Antibody , NKR-P1D Antibody , NKR-P1B Antibody

Research Area

REFERENCE

Clone Reference

Lin X et al. Cancer Biol Ther. 2019; 20 (5):666-679 Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma.
Application : IHC-P
Reactivity : Mouse
Mukherjee S et al. J Exp Clin Cancer Res. 2018; 37 (1) Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells.
Application : Neutralizing/Inhibition
Reactivity : Mouse
Krebs DL et al. J Immunol. 2012; 188 (10):5094-105 Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.
Application : FACS, Depletion
Reactivity : Mouse
Diamond MS et al. J Exp Med. 2011; 208 (10):1989-2003 Type I interferon is selectively required by dendritic cells for immune rejection of tumors.
Application : FACS, Depletion
Reactivity : Mouse
Lubinski JM et al. J Virol. 2011; 85 (7):3239-49 The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo.
Application : FACS, Depletion
Reactivity : Mouse
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REVIEW

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Clone Reference
Lin X et al. Cancer Biol Ther. 2019; 20 (5):666-679 Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma.
Application : IHC-P
Reactivity : Mouse
Mukherjee S et al. J Exp Clin Cancer Res. 2018; 37 (1) Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells.
Application : Neutralizing/Inhibition
Reactivity : Mouse
Krebs DL et al. J Immunol. 2012; 188 (10):5094-105 Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.
Application : FACS, Depletion
Reactivity : Mouse
Diamond MS et al. J Exp Med. 2011; 208 (10):1989-2003 Type I interferon is selectively required by dendritic cells for immune rejection of tumors.
Application : FACS, Depletion
Reactivity : Mouse
Lubinski JM et al. J Virol. 2011; 85 (7):3239-49 The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo.
Application : FACS, Depletion
Reactivity : Mouse
Awasthi A et al. J Exp Med. 2010; 207 (9):1923-38 Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
Application : FACS, Activation
Reactivity : Mouse
Coudert JD et al. Blood. 2008; 111 (7) Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways.
Application : FACS, IP
Reactivity : Mouse
Ljutic B et al. J Immunol.2005 2005; 174 (8):4789-96 Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors.
Application : IP, Neutralizing/Inhibition
Reactivity : Mouse
Kanwar JR et al. J Natl Cancer Inst. 2001; 93 (20):1541-52 Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy.
Application : IHC-Fr, Depletion
Reactivity : Mouse
SDS
PBS.pdf
Package List Price ($)
$ 409
Custom Conjugations