NK1.1 antibody [PK136] (PE)

Cat. No. GTX01478-08
Cat. No.  GTX01478-08
Anti-NK1.1 antibody [PK136] (PE) used in Flow cytometry (FCM). GTX01478-08
GTX01478-08 FCM Image

FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-08 NK1.1 antibody [PK136] (PE).
Right panel : co-stained with NK1.1 antibody [PK136] (PE) and Mouse CD3e antibody (APC)
Left panel : co-stained with isotype control and Mouse CD3e antibody (APC)
antibody amount : 0.5 μg (5 μl)

1 / 1
Anti-NK1.1 antibody [PK136] (PE) used in Flow cytometry (FCM). GTX01478-08
This NK1.1 antibody [PK136] (PE) (GTX01478-08) is a mouse monoclonal antibody validated for detection of NK1.1 by FCM. Reactivity has been shown in Mouse.
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    PK136
  • Isotype
    IgG2a
  • Applications
    FCM
  • Reactivity
    Mouse
Summary
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB.
See all NK1.1 products

Ask