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NKX2.1 antibody [NX2.1/690]

Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906
Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906
Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906

Cat. No. GTX34906

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NX2.1/690

Isotype

 IgG1

Application

 ICC/IF, IHC-P, FACS

Reactivity

 Human, Mouse, Rat
Package
100 μg ($529)
See all NKX2.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
FACS 1-2μg/10⁶ cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Recombinant TTF-1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCH , BHC , NK2 , NK2 homeobox 1 , NKX2.1 , NKX21 , NKX2A , NMTC1 , T/EBP , TEBP , TITF1 , TTF1 , Nkx2.1

Cellular Localization

Nucleus

Background

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES

Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906

GTX34906 IHC-P Image

IHC-P analysis of human thyroid tissue using GTX34906 NKX2.1 antibody [NX2.1/690].

Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906

GTX34906 IHC-P Image

IHC-P analysis of rat lung tissue using GTX34906 NKX2.1 antibody [NX2.1/690].

Anti-NKX2.1 antibody [NX2.1/690] used in IHC (Paraffin sections) (IHC-P). GTX34906

GTX34906 IHC-P Image

IHC-P analysis of human lung adenocarcinoma tissue using GTX34906 NKX2.1 antibody [NX2.1/690].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529