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NKX2.8 antibody [NKX28/3233R]

Anti-NKX2.8 antibody [NKX28/3233R] used in Western Blot (WB). GTX02689

Cat. No. GTX02689

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 NKX28/3233R

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human
Package
100 μg ($529)
See all NKX2.8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent

Note :

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant NKX2.8 protein fragment (around aa 10-123)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NK2 homeobox 8 , NKX2.8 , NKX2H , Nkx2-9

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]

Database

Research Area

DATA IMAGES

Anti-NKX2.8 antibody [NKX28/3233R] used in Western Blot (WB). GTX02689

GTX02689 WB Image

WB analysis of various samples using GTX02689 NKX2.8 antibody [NKX28/3233R].
Lane 1 : PC3 whole cell lysate
Lane 2 : MCF-7 whole cell lysate

REFERENCE

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REVIEW

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Package List Price ($)
$ 529