APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat, Rabbit, Bovine, Dog, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide directed towards the C terminal region of human NKX2-8
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
NK2 homeobox 8,NKX2.8,NKX28,NKX2H,Nkx29
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]
Database
Research Area
DATA IMAGES
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GTX04864 WB Image
WB analysis of human heart tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 0.2-1 μg/mL
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GTX04864 WB Image
WB analysis of human fetal lung tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 1 μg/mL
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GTX04864 WB Image
WB analysis of human fetal heart tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 1 μg/mL
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GTX04864 WB Image
WB analysis of mouse heart tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 1 μg/mL
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GTX04864 WB Image
WB analysis of human placenta tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 1 μg/mL
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GTX04864 WB Image
WB analysis of human fetal liver tissue lysate using GTX04864 NKX2.8 antibody.
Dilution : 1 μg/mL
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REFERENCE
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REVIEW
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