APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 μg/mL |
5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
NALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.The immunogen is located within amino acids 110 - 160 of NALP12.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
NLR family pyrin domain containing 12 , CLR19.3 , FCAS2 , NALP12 , PAN6 , PYPAF7 , RNO , RNO2
Cellular Localization
Cytoplasm
Background
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Database
Research Area
DATA IMAGES
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GTX31418 IHC-P Image
IHC-P analysis of human brain tissue using GTX31418 NLRP12 antibody. Working concentration : 5 μg/ml
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GTX31418 IHC-P Image
IHC-P analysis of human brain tissue using GTX31418 NLRP12 antibody. Working concentration : 20 μg/ml
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GTX31418 WB Image
WB analysis of human brain tissue lysate using GTX31418 NLRP12 antibody. Working concentration : 1 μg/ml
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REFERENCE
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REVIEW
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