GeneTex
United States (US)

NLRP12 antibody

Anti-NLRP12 antibody used in IHC (Paraffin sections) (IHC-P). GTX31418
Anti-NLRP12 antibody used in Western Blot (WB). GTX31418
Anti-NLRP12 antibody used in IHC (Paraffin sections) (IHC-P). GTX31418

Cat No. GTX31418

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

120 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.The immunogen is located within amino acids 110 - 160 of NALP12.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nlr Family Pyrin Domain Containing 12,Clr19.3,Fcas2,Nalp12,Pan6,Pypaf7,Rno,Rno2,Nlrp12

Background

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES
Anti-NLRP12 antibody used in IHC (Paraffin sections) (IHC-P). GTX31418

GTX31418 IHC-P Image

IHC-P analysis of human brain tissue using GTX31418 NLRP12 antibody.
Working concentration : 5 μg/ml

Anti-NLRP12 antibody used in Western Blot (WB). GTX31418

GTX31418 WB Image

WB analysis of human brain tissue lysate using GTX31418 NLRP12 antibody.
Working concentration : 1 μg/ml

Anti-NLRP12 antibody used in IHC (Paraffin sections) (IHC-P). GTX31418

GTX31418 IHC-P Image

IHC-P analysis of human brain tissue using GTX31418 NLRP12 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329