GeneTex
United States (US)

NLRP13 antibody

GTX31990_404_ICC-IF_20180221_18121410_735.jpg
GTX31990_3124_WB_20180221_18121410_390.jpg
GTX31990_405_ICC-IF_20180221_18121410_976.jpg

Cat No. GTX31990

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
ICC/IF 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

119 kDa. ( Note )

Positive Control

K-562 Cell Slide(GTX25535) , K562 Cell Lysate(GTX27911)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.The immunogen is located within amino acids 150 - 200 of NALP13.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nlr Family Pyrin Domain Containing 13,Clr19.7,Nalp13,Nod14,Pan13,Nlrp13

Background

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]

Database

DATA IMAGES
GTX31990_404_ICC-IF_20180221_18121410_735.jpg

GTX31990 ICC/IF Image

ICC/IF analysis of K562 cells using GTX31990 NLRP13 antibody.
Working concentration : 2.5 μg/ml

GTX31990_3124_WB_20180221_18121410_390.jpg

GTX31990 WB Image

WB analysis of K562 cell lysate using GTX31990 NLRP13 antibody.
Working concentration : 1 μg/ml

GTX31990_405_ICC-IF_20180221_18121410_976.jpg

GTX31990 ICC/IF Image

ICC/IF analysis of K562 cells using GTX31990 NLRP13 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329