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NLRX1 antibody

Anti-NLRX1 antibody used in Western Blot (WB). GTX84999
Anti-NLRX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX84999
Anti-NLRX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX84999

Cat. No. GTX84999

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all NLRX1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

108 kDa. ( Note )

Positive Control

Rat Spleen Tissue Lysate(GTX27945)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NLRX1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NLRX1.The immunogen is located within amino acids 70 - 120 of NLRX1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NLR family member X1 , CLR11.3 , DLNB26 , NOD26 , NOD5 , NOD9

Cellular Localization

Mitochondrion outer membrane

Background

NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production.

Database

Research Area

DATA IMAGES

Anti-NLRX1 antibody used in Western Blot (WB). GTX84999

GTX84999 WB Image

WB analysis of rat spleen tissue lysate using GTX84999 NLRX1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-NLRX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX84999

GTX84999 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX84999 NLRX1 antibody.
Working concentration : 20 μg/ml

Anti-NLRX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX84999

GTX84999 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX84999 NLRX1 antibody.
Working concentration : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399