APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
5 - 10 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat, Dog, Hamster, Monkey, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda, Xenopus, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human NMBR.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375879
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
neuromedin B receptor , BB1 , BB1R , NMBR
Cellular Localization
Cell membrane
Background
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Database
Research Area
DATA IMAGES
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GTX71681 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX71681 NMBR antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71681 IHC-P Image
IHC-P analysis of human brain, olfactory bulb tissue using GTX71681 NMBR antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71681 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX71681 NMBR antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71681 IHC-P Image
IHC-P analysis of human testis tissue using GTX71681 NMBR antibody. Antigen retrieval : Heat-induced antigen retrieval Dilution : 16 μg/ml
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GTX71681 IHC-P Image
IHC-P analysis of human lung, carcinoma tissue using GTX71681 NMBR antibody. Antigen retrieval : Heat-induced antigen retrieval Dilution : 16 μg/ml
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REFERENCE
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REVIEW
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