*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
mouse brain , mouse fetal brain , rat brain
Human, Dog(>80% identity)
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1.23 mg/ml (Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse NMDAR1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Glutamate Receptor, Ionotropic, Nmda1 (Zeta 1),Glun1,Glurdelta1,Glurzeta1,M100174,Nmd-R1,Nmdar1,Nr1,Nmdar,Rgsc174,Grin1
Cell membrane; Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane , postsynaptic cell membrane , postsynaptic density
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Modulated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
GTX133097 IHC-P Image
NMDAR1 antibody detects NMDAR1 protein at cytoplasm in rat brain by immunohistochemical analysis.
Sample: Paraffin-embedded rat brain.
NMDAR1 antibody (GTX133097) diluted at 1:400.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX133097 IHC-Fr Image
NMDAR1 antibody detects NMDAR1 protein expression by immunohistochemical analysis.
Sample: Frozen sectioned adult mouse retina.
Green: NMDAR1 protein stained by NMDAR1 antibody (GTX133097) diluted at 1:250.
Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] (GTX631836) diluted at 1:250.
Blue: Fluoroshield with DAPI (GTX30920).
GTX133097 ICC/IF Image
NMDAR1 antibody detects NMDAR1 protein at synaptic vesicles by immunofluorescent analysis.
Sample: DIV9 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min.
Green: NMDAR1 protein stained by NMDAR1 antibody (GTX133097) diluted at 1:500.
Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] (GTX631836) diluted at 1:500.
Blue:Fluoroshield with DAPI (GTX30920).
GTX133097 WB Image
Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with NMDAR1 antibody (GTX133097) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.