GeneTex
United States (US)

NMDAR2B antibody

Cat No. GTX14400

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

For WB: Use at a concentration of 0.5-2.0 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

166 kDa. ( Note )

Positive Control

Rat brain microsomal protein preparation
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.6, containing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Amino acids 1437-1456 of mature mouse NR2B or 1463-1482 of NR2B precursor; signal is amino acid residues 1-26 [KFNGSSNGHV-YEKLSSIESDV].

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glutamate Receptor, Ionotropic, Nmda2B (Epsilon 2),Aw490526,Glun2B,Glurepsilon2,Nr2B,Nmdar2B,Grin2B

Background

NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA).

Database

Research Area

Package List Price ($)
$ 319