*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , H1299 , HeLa , HepG2 , Raji
Mouse, Rat, Bovine, Pig(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Recombinant protein encompassing a sequence within the C-terminus region of human NOD1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, NOD1 antibody, "NLR family, CARD domain containing 1 antibody", "caspase recruitment domain family, member 4 antibody", caspase recruitment domain-containing protein 4 antibody, nucleotide-binding oligomerization domain-containing protein 1 antibody, "nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1 antibody", nucleotide-binding oligomerization domain containing 1 antibody
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq]
GTX108811 ICC/IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NOD1(GTX108811) antibody at 1:200 dilution.
GTX108811 WB Image
Sample (30 ug of whole cell lysate)
7.5% SDS PAGE
GTX108811 diluted at 1:1000