APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NOD1 (NP_006083.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
nucleotide binding oligomerization domain containing 1 , CARD4 , CLR7.1 , NLRC1
Cellular Localization
Cytoplasm,Cell membrane,Apical cell membrane
Background
This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
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GTX54595 IHC-P Image
IHC-P analysis of rat ovary tissue using GTX54595 NOD1 antibody.
Dilution : 1:100
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GTX54595 IHC-P Image
IHC-P analysis of human mammary cancer tissue using GTX54595 NOD1 antibody.
Dilution : 1:100
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GTX54595 WB Image
WB analysis of various sample lysates using GTX54595 NOD1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX54595 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX54595 NOD1 antibody.
Dilution : 1:100
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REFERENCE
There are currently no references for NOD1 antibody (GTX54595). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NOD1 antibody (GTX54595). Be the first to share your experience with this product.
