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NOTCH1 antibody [mN1A]

Cat. No. GTX00470

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 mN1A

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP

Reactivity

 Human, Mouse
Package
100 μg ($339)
See all NOTCH1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

271 kDa. ( Note )

Product Note

This antibody recognizes intracellular domain of Notch 1 protein, mainly its activated form. The unprocessed Notch 1 protein is recognized with lower affinity.
We do not recommend use of this product for Rat samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

GST fusion protein containing cdc10-NCR region of mouse Notch1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

notch 1 , 9930111A19Rik , Mis6 , N1 , Tan1 , lin-12

Cellular Localization

Cell membrane

Database

Research Area

REFERENCE

Clone Reference

N Marcel et al. Elife 2016; 5:e14023 Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells
Application : ICC/IF, IP
LR Perumalsamy et al. Sci Signal 2012; 5 (234):ra53 Distinct Spatial and Molecular Features of Notch Pathway Assembly in Regulatory T Cells
Application : IP
F Jundt et al. Leukemia 2008; 22 (8):1587-94 Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma
Application : WB, IHC-P, IP
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339