GeneTex
  • Country / Location Selection

United States (US)

NOTCH3 antibody [C3], C-term

Anti-NOTCH3 antibody [C3], C-term used in Western Blot (WB). GTX104681

Cat No. GTX104681

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

244 kDa. ( Note )

Positive Control

HeLa

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

5.26 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NOTCH3. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

notch receptor 3 , CADASIL , CADASIL1 , CASIL , IMF2 , LMNS

Cellular Localization

Cell membrane; Single-pass type I membrane protein , Notch 3 intracellular domain: Nucleus

Background

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]

Database

Research Area

DATA IMAGES
Anti-NOTCH3 antibody [C3], C-term used in Western Blot (WB). GTX104681

GTX104681 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
5% SDS PAGE
GTX104681 diluted at 1:1000

REFERENCE
There are currently no references for NOTCH3 antibody [C3], C-term (GTX104681). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NOTCH3 antibody [C3], C-term (GTX104681). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169