NOX2 / gp91phox peptide is used for blocking the activity of NOX2 / gp91phox antibody (catalog number GTX31930). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl), 0.1% BSA, 0.02% sodium azide
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
200 μg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cytochrome B-245 Beta Chain , Amcbx2 , Cgd , Gp91-1 , Gp91-Phox , Gp91Phox , Imd34 , Nox2 , P91-Phox , Cybb
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]