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NOX2 / gp91phox blocking peptide

Cat No. GTX31930-PEP

Application

Neutralizing/Inhibition
Package
50 μg ($139)
PRODUCT

Summary

NOX2 / gp91phox peptide is used for blocking the activity of NOX2 / gp91phox antibody (catalog number GTX31930). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl), 0.1% BSA, 0.02% sodium azide

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Cytochrome B-245 Beta Chain , Amcbx2 , Cgd , Gp91-1 , Gp91-Phox , Gp91Phox , Imd34 , Nox2 , P91-Phox , Cybb

Background

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for NOX2 / gp91phox blocking peptide (GTX31930-PEP). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for NOX2 / gp91phox blocking peptide (GTX31930-PEP). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139