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NOXO1 antibody [C2C3], C-term

Anti-NOXO1 antibody [C2C3], C-term used in Western Blot (WB). GTX108043

Cat. No. GTX108043

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Rat
Package
100 μl ($399),
25 μl ($169)
See all NOXO1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

HCT116

Predict Reactivity

Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NOXO1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1241117

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NADPH oxidase organizer 1 , P41NOX , P41NOXA , P41NOXB , P41NOXC , SH3PXD5 , SNX28

Cellular Localization

Isoform 3: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Background

NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-NOXO1 antibody [C2C3], C-term used in Western Blot (WB). GTX108043

GTX108043 WB Image

Sample (30 ug of whole cell lysate)
A: HCT116 10% SDS PAGE
GTX108043 diluted at 1:1000

REFERENCE

Application Reference

Kang Y et al. ACS Nano 2020; (Epub) Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.
Application : WB
Reactivity : Rat
Dvoriantchikova G et al. Invest Ophthalmol Vis Sci 2012; 53 (6) : 2823-30 Neuronal NAD(P)H oxidases contribute to ROS production and mediate RGC death after ischemia.
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169