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NPR-C antibody

Orthogonal
Anti-NPR-C antibody used in Western Blot (WB). GTX64458
Anti-NPR-C antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64458
Anti-NPR-C antibody used in Western Blot (WB). GTX64458
Anti-NPR-C antibody used in Western Blot (WB). GTX64458

Cat. No. GTX64458

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all NPR-C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 272-541 of human NPR3 (NP_001191304.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2888599

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

natriuretic peptide receptor 3 , ANP-C , ANPR-C , ANPRC , C5orf23 , GUCY2B , NPR-C , NPRC

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-NPR-C antibody used in Western Blot (WB). GTX64458

GTX64458 WB Image

WB analysis of various sample lysates using GTX64458 NPR-C antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NPR-C antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64458

GTX64458 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX64458 NPR-C antibody.
Blue : DAPI
Dilution : 1:100

Anti-NPR-C antibody used in Western Blot (WB). GTX64458

GTX64458 WB Image

Orthogonal

The data was published in the journal Cancers (Basel) in 2019.PMID: 31614775

Anti-NPR-C antibody used in Western Blot (WB). GTX64458

GTX64458 WB Image

The data was published in the journal Cancers (Basel) in 2019.PMID: 31614775

REFERENCE

Application Reference

Re Cecconi AD et al. Cancers (Basel) 2019; 11 (10) Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399