NR0B2 antibody [OTI7B5]

Cat. No. GTX04884

Host	Mouse
Clonality	Monoclonal
Clone Name	OTI7B5
Isotype	IgG2a
Application	WB, IHC-P
Reactivity	Human
Package	100 μl ($539)

See all NR0B2 products

Datasheet

View product citations for antibody GTX04884 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:2000
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human recombinant protein of human NR0B2 (NP_068804) produced in E.coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NR0B2,SHP,SHP1,nuclear receptor subfamily 0 group B member 2

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]

Database

Gene ID: 8431 NR0B2
UniProt: Q15466 NR0B2

Research Area

DATA IMAGES

GTX04884 IHC-P Image

IHC-P analysis of human liver carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human liver tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human breast adenocarcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human endometrium tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human bladder tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human bladder carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human lymphoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human colon tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human colon adenocarcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human ovary adenocarcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human kidney carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human prostate tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human kidney tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human pancreas carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human endometrium adenocarcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 WB Image

WB analysis of HEK293T cells with/without human NR0B2 transfection using GTX04884 NR0B2 antibody [OTI7B5].
Loading : 5 μg

GTX04884 IHC-P Image

IHC-P analysis of human thyroid carcinoma tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

GTX04884 IHC-P Image

IHC-P analysis of human thyroid tissue using GTX04884 NR0B2 antibody [OTI7B5].
Antigen retrieval : Heat mediated Tris-EDTA, pH8.0
Dilution: 1:150

REFERENCE

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REVIEW

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Package	List Price ($)
100 μl	$ 539
Qty

NR0B2 antibody [OTI7B5]

Cat. No. GTX04884

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Calculated MW

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

Note

TARGET

Synonyms

Cellular Localization

Background

Database

Research Area

DATA IMAGES

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

GTX04884 WB Image

GTX04884 IHC-P Image

GTX04884 IHC-P Image

REFERENCE

REVIEW

Product

Research

Support

Company

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