*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Rat, Bovine, Dog, Pig, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Panda(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 16 amino acid peptide from ligand-binding domain of human NR0B2.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
nuclear receptor subfamily 0 group B member 2 , NR0B2 , SHP , SHP1
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]
GTX70897 IHC-P Image
IHC-P analysis of human liver, hepatocytes tissue using GTX70897 NR0B2 antibody.
Antigen retrieval : Heat-induced antigen retrieval