GeneTex
United States (US)

NSD2 antibody

GTX64491_20180530_IHC-P_18121411_396.jpg
GTX64491_20180530_IHC-P_1_18121411_565.jpg
GTX64491_20180530_WB_18121411_993.jpg

Cat No. GTX64491

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

152 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-240 of human WHSC1 (NP_579877.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nuclear Receptor Binding Set Domain Protein 2,Kmt3F,Kmt3G,Mmset,Reiibp,Trx5,Whs,Whsc1,Nsd2

Background

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX64491_20180530_IHC-P_18121411_396.jpg

GTX64491 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64491 NSD2 antibody.
Dilution : 1:100

GTX64491_20180530_IHC-P_1_18121411_565.jpg

GTX64491 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64491 NSD2 antibody.
Dilution : 1:100

GTX64491_20180530_WB_18121411_993.jpg

GTX64491 WB Image

WB analysis of various samples using GTX64491 NSD2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319