APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
16 - 24 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Gibbon, Gorilla(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 17 amino acid peptide from C-terminus of human NTSR2.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375583
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
neurotensin receptor 2 , NTR2 , NTSR2 , Neurotensin Receptor 2
Cellular Localization
Cell membrane
Background
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX71151 IHC-P Image
IHC-P analysis of brain, medulla tissue using GTX71151 NTSR2 antibody.
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GTX71151 IHC-P Image
IHC-P analysis of brain, substantia nigra tissue using GTX71151 NTSR2 antibody.
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GTX71151 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX71151 NTSR2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71151 IHC-P Image
IHC-P analysis of human brain, protoplasmic astrocyte tissue using GTX71151 NTSR2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71151 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX71151 NTSR2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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