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NUDT15 antibody

Anti-NUDT15 antibody used in Western Blot (WB). GTX32759
Anti-NUDT15 antibody used in IHC (Paraffin sections) (IHC-P). GTX32759
Anti-NUDT15 antibody used in IHC (Paraffin sections) (IHC-P). GTX32759

Cat No. GTX32759

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

nudix hydrolase 15 , MTH2 , NUDT15D

Background

This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016]

Database

Research Area

DATA IMAGES

Anti-NUDT15 antibody used in Western Blot (WB). GTX32759

GTX32759 WB Image

WB analysis of various samples using GTX32759 NUDT15 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NUDT15 antibody used in IHC (Paraffin sections) (IHC-P). GTX32759

GTX32759 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32759 NUDT15 antibody.
Dilution : 1:100

Anti-NUDT15 antibody used in IHC (Paraffin sections) (IHC-P). GTX32759

GTX32759 IHC-P Image

IHC-P analysis of human liver tissue using GTX32759 NUDT15 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329