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NUMB antibody [N1N3]

Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715
Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715
Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715

Cat. No. GTX111715

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all NUMB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

A431 , mouse lung , rat lung

Predict Reactivity

Zebrafish, Bovine, Chicken, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.79 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human NUMB. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1951040

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527

Cellular Localization

Membrane; Peripheral membrane protein

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715

GTX111715 WB Image

Mouse tissue extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with NUMB antibody [N1N3] (GTX111715) diluted at 1:1000.

Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715

GTX111715 WB Image

Sample (30 ug of whole cell lysate)
A: A431 (GTX27909)
7.5% SDS PAGE
GTX111715 diluted at 1:1000

Anti-NUMB antibody [N1N3] used in Western Blot (WB). GTX111715

GTX111715 WB Image

Rat tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with NUMB antibody [N1N3] (GTX111715) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169